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NCKIPSD Antibody - middle region: Biotin (ARP59509_P050-Biotin)

Product Specifications

Gene Name

NCK interacting protein with SH3 domain

Gene Aliases

DIP, DIP1, ORF1, WISH, VIP54, AF3P21, SPIN90, WASLBP

Gene ID

51517

Swiss Prot

Q9NZQ3

Accession Number

NP_909119

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human NCKIPSD

Target

The protein encoded by this gene is localized exclusively in the cell nucleus. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation. The gene is involved in therapy-related leukemia by a chromosomal translocation t (3;11) (p21; q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing occurs in this locus and two transcript variants encoding distinct isoforms have been identified.

Partner Proteins

SORBS3; PSMD9; YWHAB; UBC; GRB2; CRK; FASLG; KHDRBS1; STAC; DMRTB1; ARHGEF7; BAIAP2; YWHAG; NCK2; DLG4; MAPK3; NCK1; WAS; DIAPH2; ITGB1; DIAPH3

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

79kDa

Shipping Conditions

Wet Ice

Protein Length

715

NCBI Gene Symbol

NCKIPSD

Protein Name

NCK-interacting protein with SH3 domain

Nucleotide Accession Number

NM_184231

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