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SYT12 Antibody - N-terminal region : Biotin (ARP59489_P050-Biotin)

Product Specifications

Gene Name

Synaptotagmin XII

Gene Aliases

SYT11, sytXII

Gene ID

91683

Swiss Prot

Q8IV01

Accession Number

NP_808878

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SYT12

Target

This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Studies of the orthologous gene in rat have shown that the encoded protein selectively modulates spontaneous synaptic-vesicle exocytosis and may also be involved in regulating calcium independent secretion in nonneuronal cells. Alternative splicing results in multiple transcript variants. The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature.

Partner Proteins

UBC

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

SYT12 is strongly supported by BioGPS gene expression data to be expressed in PANC1

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 92%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 93%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

46kDa

Shipping Conditions

Wet Ice

Product Datasheet

Anti-SYT12 (ARP59489_P050-Biotin) antibody

Protein Length

421

NCBI Gene Symbol

SYT12

NCBI GB Accession Number

SYT12

Host or Source

Rabbit

Protein Name

Synaptotagmin-12

Nucleotide Accession Number

NM_177963

Peptide Sequence

AEAREKRVPAWNAQRASTRGPPSRKGSLSIEDTFESISELGPLELMGREL

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