NUMB Antibody - middle region : Biotin (ARP59434_P050-Biotin)
Selected Variant
ARP59434_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Numb homolog (Drosophila)
Gene Aliases
S171, C14orf41, c14_5527
Gene ID
8650
Swiss Prot
P49757-4
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human NUMB
Target
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene.
Partner Proteins
TP53; PRKCA; PRKCZ; PRKCE; PRKCB; UBC; SIAH1; RPL3; EGFR; NOTCH1; MDM2; APP; Trp53; Jun; EPS15; Lnx1; ITCH; GLI1; LNX2; AP2A2; PRKCH; DPYSL2; AP2A1; ITGB2; L1CAM; PRKCG; PRKCD; ITGB3; ITGB5; Eps15l1; RALBP1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Yeast: 91%; Zebrafish: 83%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
64kDa
Shipping Conditions
Wet Ice
Protein Length
592
NCBI Gene Symbol
NUMB
NCBI GB Accession Number
NUMB
Host or Source
Rabbit
Protein Name
Protein numb homolog
Peptide Sequence
VGSSVAPGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQG
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