Numb Antibody - C-terminal region : HRP (ARP59433_P050-HRP)
Selected Variant
ARP59433_P050-HRP
Size: 100 µL
Product Specifications
Gene Name
Numb gene homolog (Drosophila)
Gene Aliases
Nb, m-num
Gene ID
18222
Swiss Prot
Q9QZS3-2
Accession Number
NP_035079
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Target
Numb plays a role in the process of neurogenesis. It is required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. It is not required for the proliferation of neural progenitor cells before the onset of neurogenesis. It is also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. It may also mediate local repair of brain ventricular wall damage.
Partner Proteins
Igsf5; Eed; Grin1; Cdh2; Cdh1; Ctnnb1; Ctnna1; Lnx2; Lnx1; Notch1; Eps15; Ehd1; Ehd4
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 93%; Rat: 93%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
66kDa
Shipping Conditions
Wet Ice
Protein Length
604
NCBI Gene Symbol
NUMB
NCBI GB Accession Number
Numb
Host or Source
Rabbit
Protein Name
Protein numb homolog
Nucleotide Accession Number
NM_010949
Peptide Sequence
ASGNRHAEVPPGTCPVDPFEAQWAALESKSKQRTNPSPTNPFSSDLQKTF
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