UFD1 Antibody - middle region : FITC (ARP59424_P050-FITC)

Product Specifications

Gene Name

Ubiquitin recognition factor in ER associated degradation 1

Gene Aliases

UFD1L

Gene ID

7353

Swiss Prot

Q92890

Accession Number

NP_005650

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human UFD1L

Target

The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18.

Partner Proteins

HUWE1; YOD1; VCP; UBC; SHFM1; SUZ12; BTRC; EZH2; PDCD4; NPLOC4; NFKBIA; NUB1; NEDD8; CAV1; ADRB2; FAF1; TXLNA; UNC45A; VPS33B; UBE3A; UBE2N; PSMD7; SPRTN; UBXN6; GZMK; ERLIN2; ITPR1; PPHLN1; ANAPC2; TIAM2; TAF1C; TP53; SNX1; MASP1; PIK3CA; NGFR; IGHM; F13

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

UFD1L is supported by BioGPS gene expression data to be expressed in MCF7

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.