FBXL12 Antibody - C-terminal region : FITC (ARP59409_P050-FITC)
Selected Variant
ARP59409_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
F-box and leucine-rich repeat protein 12
Gene Aliases
Fbl12
Gene ID
54850
Swiss Prot
Q9NXK8
Accession Number
NP_060173
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human FBXL12
Target
Members of the F-box protein family, such as FBXL12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]) .
Partner Proteins
LNX1; DOCK8; PRAME; STYX; HSP90AA1; CUL1; SKP1; RNF32; ECSIT; MAST1; CDC37; PSEN2; PSEN1; APOE; A2M; UBC; COPS6; RBX1; CDKN1C; JUN; FXYD3; SMAD1; TGFBR1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 86%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
37kDa
Shipping Conditions
Wet Ice
Protein Length
326
NCBI Gene Symbol
FBXL12
NCBI GB Accession Number
FBXL12
Host or Source
Rabbit
Protein Name
F-box/LRR-repeat protein 12
Nucleotide Accession Number
NM_017703
Peptide Sequence
PTEILSSCLTMPKLRVLELQGLGWEGQEAEKILCKGLPHCMVIVRACPKE
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