UBA6 Antibody: Biotin (ARP59383_P050-Biotin)
Product Specifications
Gene Name
Ubiquitin-like modifier activating enzyme 6
Gene Aliases
E1-L2, MOP-4, UBE1L2
Gene ID
55236
Swiss Prot
A0AVT1
Accession Number
NP_060697
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the following sequence SNKVVQTDETARKPDHVPISSEDERNAIFQLEKAILSNEATKSDLQMAVL
Target
Modification of proteins with ubiquitin (UBB; MIM 191339) or ubiquitin-like proteins controls many signaling networks and requires a ubiquitin-activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3) . UBE1L2 is an E1 enzyme that initiates the activation and conjugation of ubiquitin-like proteins (Jin et al., 2007 [PubMed 17597759]) .[supplied by OMIM, Mar 2008]
Partner Proteins
HMBOX1; UBC; UBE2L3; UBE2G2; UBE2D3; UBE2D2; UBE2D1; UBE2Z; UBE2T; UBE2S; H2AFV; OGFOD1; TRNT1; TWF2; FKBP9; EHD1; AHCYL1; NUBP2; PDCD6IP; GNPDA1; OXSR1; NOL3; LIMD1; XPNPEP1; RAD23B; RAD23A; PYGB; PGGT1B; HEXA; CTPS1; SMAD9; VPS26B; USP48; UBE4B; NPEPPS
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 86%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 86%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
118 kDa
Shipping Conditions
Wet Ice
Protein Length
1052
NCBI Gene Symbol
UBA6
Protein Name
Ubiquitin-like modifier-activating enzyme 6
Nucleotide Accession Number
NM_018227
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