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ZRANB1 Antibody - C-terminal region : FITC (ARP59341_P050-FITC)

Product Specifications

Gene Name

Zinc finger, RAN-binding domain containing 1

Gene Aliases

TRABID

Gene ID

54764

Swiss Prot

Q9UGI0

Accession Number

NP_060050

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human ZRANB1

Target

ZRANB1 is a positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains.ZRANB1 acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription. ZRANB1 may also modulate TNF-alpha signaling.

Partner Proteins

Btrc; UBC; CORO7; STRIP1; CTTNBP2; CTTNBP2NL; STRN3; STRN4; HECTD1; SLMAP; STRN; UBE2S; TRAF6; Apc; PGAM5; STRIP2; CACYBP; FGFR1OP2; MOB4; BICD2; FBXW11; KEAP1; GCC2; MAP4K4; HERC2; ALDH18A1; PPP2R1B

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

81kDa

Shipping Conditions

Wet Ice

Protein Length

708

NCBI Gene Symbol

ZRANB1

NCBI GB Accession Number

ZRANB1

Host or Source

Rabbit

Protein Name

Ubiquitin thioesterase ZRANB1

Nucleotide Accession Number

NM_017580

Peptide Sequence

GAGANLNTDDDVTITFLPLVDSERKLLHVHFLSAQELGNEEQQEKLLREW

Frequently Asked Questions

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