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USP1 Antibody - C-terminal region : Biotin (ARP59299_P050-Biotin)

Selected Variant

ARP59299_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Ubiquitin specific peptidase 1

Gene Aliases

UBP

Gene ID

7398

Swiss Prot

O94782

Accession Number

NP_003359

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human USP1

Target

This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized.

Partner Proteins

WDR48; UBC; DTX3; TRIM46; PHF7; TRAF6; UBE2A; UNC45A; VPS36; WDR5; VPS26A; CSE1L; PHLPP1; PCNA; SUMO2; ATAD5; ID2; FANCD2; USP1; DSG1; DSC1; CALML3; ANXA2P2; ALDH16A1; CALML5; PHLPP2; TAGLN2; USP4; PKP1; MYH9; LYZ; LGALS7; KRT17; KRT4; KPNA1; JUP; HSPB1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 86%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 93%; Rat: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

88kDa

Shipping Conditions

Wet Ice

Protein Length

785

NCBI Gene Symbol

USP1

NCBI GB Accession Number

USP1

Host or Source

Rabbit

Protein Name

Ubiquitin carboxyl-terminal hydrolase 1

Nucleotide Accession Number

NM_003368

Peptide Sequence

SETSDTTGTHESDRNKESSDQTGINISGFENKISYVVQSLKEYEGKWLLF

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