USP1 Antibody - C-terminal region : Biotin (ARP59299_P050-Biotin)
Selected Variant
ARP59299_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Ubiquitin specific peptidase 1
Gene Aliases
UBP
Gene ID
7398
Swiss Prot
O94782
Accession Number
NP_003359
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human USP1
Target
This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized.
Partner Proteins
WDR48; UBC; DTX3; TRIM46; PHF7; TRAF6; UBE2A; UNC45A; VPS36; WDR5; VPS26A; CSE1L; PHLPP1; PCNA; SUMO2; ATAD5; ID2; FANCD2; USP1; DSG1; DSC1; CALML3; ANXA2P2; ALDH16A1; CALML5; PHLPP2; TAGLN2; USP4; PKP1; MYH9; LYZ; LGALS7; KRT17; KRT4; KPNA1; JUP; HSPB1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 92%; Dog: 86%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 93%; Rat: 92%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
88kDa
Shipping Conditions
Wet Ice
Protein Length
785
NCBI Gene Symbol
USP1
NCBI GB Accession Number
USP1
Host or Source
Rabbit
Protein Name
Ubiquitin carboxyl-terminal hydrolase 1
Nucleotide Accession Number
NM_003368
Peptide Sequence
SETSDTTGTHESDRNKESSDQTGINISGFENKISYVVQSLKEYEGKWLLF
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