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SERPINB6 Antibody - middle region : FITC (ARP59249_P050-FITC)

Selected Variant

ARP59249_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Serpin peptidase inhibitor, clade B (ovalbumin), member 6

Gene Aliases

CAP, PI6, PTI, PI-6, SPI3, DFNB91, MSTP057

Gene ID

5269

Swiss Prot

P35237

Accession Number

NP_004559

Host

Rabbit

Reactivity

Human, Cow

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SERPINB6

Target

The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin (ov) -serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene.

Partner Proteins

SUMO2; C16orf70; AHCY; CRK; UBC; F10; PLAU; F2; PROC; PLG; KLK2

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 79%; Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

41kDa

Shipping Conditions

Wet Ice

Protein Length

376

NCBI Gene Symbol

SERPINB6

NCBI GB Accession Number

SERPINB6

Host or Source

Rabbit

Protein Name

Serpin B6

Nucleotide Accession Number

NM_004568

Peptide Sequence

LVLVNAVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMFKQSTFKKTY

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