A2M Antibody - N-terminal region: Biotin (ARP59224_P050-Biotin)
Product Specifications
Gene Name
Alpha-2-macroglobulin
Gene Aliases
A2MD, CPAMD5, FWP007, S863-7
Gene ID
2
Swiss Prot
P01023
Accession Number
NP_000005
Host
Rabbit
Reactivity
Human
Target
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.
Partner Proteins
MAPK6; CDK7; CDK11A; HIPK1; FBXO6; CFTR; TP63; TGM2; IFIT3; DNAJB1; GCDH; FARSA; ENO2; ELAVL3; CYP2C18; CYP2C8; ATP1A1; APP; APOE; ACTB; A2M; RNF32; SWSAP1; TRAPPC5; EVI5L; EGLN2; IGSF8; PRAM1; MLST8; STAMBPL1; RETN; FBXL12; ECSIT; FIS1; EXOSC1; IFIT5; NC
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
161kDa
Shipping Conditions
Wet Ice
Protein Length
1474
NCBI Gene Symbol
A2M
Protein Name
Alpha-2-macroglobulin
Nucleotide Accession Number
NM_000014
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