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TIMP3 Antibody - N-terminal region : FITC (ARP59183_P050-FITC)

Selected Variant

ARP59183_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

TIMP metallopeptidase inhibitor 3

Gene Aliases

SFD, K222, K222TA2, HSMRK222

Gene ID

7078

Swiss Prot

P35625

Accession Number

NP_000353

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TIMP3

Target

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM) . Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.

Partner Proteins

AGTR2; ADAM17; EFEMP1; MMP14; MMP13; KDR; MMP3; MMP9; MMP2

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

22kDa

Shipping Conditions

Wet Ice

Protein Length

211

NCBI Gene Symbol

TIMP3

NCBI GB Accession Number

TIMP3

Host or Source

Rabbit

Protein Name

Metalloproteinase inhibitor 3

Nucleotide Accession Number

NM_000362

Peptide Sequence

MTPWLGLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKK

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