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IL17A Antibody - N-terminal region : FITC (ARP59132_P050-FITC)

Selected Variant

ARP59132_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Interleukin 17A

Gene Aliases

IL17, CTLA8, IL-17, CTLA-8, IL-17A

Gene ID

3605

Swiss Prot

Q16552

Accession Number

NP_002181

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Goat, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human IL17A

Target

The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO) . High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Partner Proteins

DPH2; TRAF3IP2; TRAF6; IL17RA; IL17A

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 83%; Dog: 85%; Goat: 83%; Horse: 77%; Human: 100%; Pig: 83%; Rabbit: 92%; Rat: 75%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

15kDa

Shipping Conditions

Wet Ice

Protein Length

155

NCBI Gene Symbol

IL17A

NCBI GB Accession Number

IL17A

Host or Source

Rabbit

Protein Name

Interleukin-17A

Nucleotide Accession Number

NM_002190

Peptide Sequence

MTPGKTSLVSLLLLLSLEAIVKAGITIPRNPGCPNSEDKNFPRTVMVNLN

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