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IL17A Antibody - N-terminal region : FITC (ARP59132_P050-FITC)

Product Specifications

Gene Name

Interleukin 17A

Gene Aliases

IL17, CTLA8, IL-17, CTLA-8, IL-17A

Gene ID

3605

Swiss Prot

Q16552

Accession Number

NP_002181

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Goat, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human IL17A

Target

The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO) . High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Partner Proteins

DPH2; TRAF3IP2; TRAF6; IL17RA; IL17A

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 83%; Dog: 85%; Goat: 83%; Horse: 77%; Human: 100%; Pig: 83%; Rabbit: 92%; Rat: 75%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

15kDa

Shipping Conditions

Wet Ice

Product Datasheet

Anti-IL17A (ARP59132_P050-FITC) antibody

Protein Length

155

NCBI Gene Symbol

IL17A

NCBI GB Accession Number

IL17A

Host or Source

Rabbit

Protein Name

Interleukin-17A

Nucleotide Accession Number

NM_002190

Peptide Sequence

MTPGKTSLVSLLLLLSLEAIVKAGITIPRNPGCPNSEDKNFPRTVMVNLN

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