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RNF128 Antibody - C-terminal region : HRP (ARP59127_P050-HRP)

Selected Variant

ARP59127_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Ring finger protein 128, E3 ubiquitin protein ligase

Gene Aliases

GRAIL

Gene ID

79589

Swiss Prot

Q8TEB7-2

Accession Number

NP_078815

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human RNF128

Target

RNF128 is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of RNF128 in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of RNF128 was observed in anergic CD4 (+) T cells, which suggested a role in the induction of anergic phenotype.

Partner Proteins

CEP76; APPBP2; TP53; UBE2H; UBE2E1; UBE2D1; Arhgdia; Arhgdib; RNF128; UBE2T; UBE2I; UBE2N; CD40LG; OTUB1; USP8

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

RNF128 is supported by BioGPS gene expression data to be expressed in COLO205

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 100%; Guinea Pig: 79%; Horse: 93%; Human: 100%; Mouse: 85%; Pig: 93%; Rabbit: 93%; Rat: 92%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

44kDa

Shipping Conditions

Wet Ice

Protein Length

402

NCBI Gene Symbol

RNF128

NCBI GB Accession Number

RNF128

Host or Source

Rabbit

Protein Name

E3 ubiquitin-protein ligase RNF128

Nucleotide Accession Number

NM_024539

Peptide Sequence

PMCKCDILKALGIEVDVEDGSVSLQVPVSNEISNSASSHEEDNRSETASS

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