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SELE Antibody - N-terminal region : FITC (ARP59109_P050-FITC)

Product Specifications

Gene Name

Selectin E

Gene Aliases

ELAM, ESEL, CD62E, ELAM1, LECAM2

Gene ID

6401

Swiss Prot

P16581

Accession Number

NP_000441

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SELE

Target

The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.

Partner Proteins

LGALS3BP; SELL; SERPING1; PXN; PTK2; GLG1; SELPLG; FLNA; VCL; PTPN11; PLCG1; CD44; ACTN2; TLN1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

SELE is supported by BioGPS gene expression data to be expressed in A549

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 86%; Guinea Pig: 86%; Horse: 79%; Human: 100%; Mouse: 79%; Rabbit: 79%; Rat: 86%; Sheep: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

64kDa

Shipping Conditions

Wet Ice

Protein Length

610

NCBI Gene Symbol

SELE

NCBI GB Accession Number

SELE

Host or Source

Rabbit

Protein Name

E-selectin

Nucleotide Accession Number

NM_000450

Peptide Sequence

WVWVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREKDVGMWNDERC

Frequently Asked Questions

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