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CD4 Antibody - C-terminal region : Biotin (ARP59105_P050-Biotin)

Selected Variant

ARP59105_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

CD4 molecule

Gene Aliases

IMD79, OKT4D, CD4mut

Gene ID

920

Swiss Prot

P01730

Accession Number

NP_000607

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human CD4

Target

This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Partner Proteins

Env; RANBP9; vpu; ADRB2; UBC; CXCR4; UBL7; ABCB1; INPPL1; VCP; HGS; LCK; NR3C1; STUB1; TUBB; MYL12A; DHRS2; LRPPRC; FARSB; EIF3I; EIF3D; EIF3C; EIF3B; VIM; VDAC3; VDAC2; VDAC1; SSRP1; RPS19; RPS12; RPS10; RPS9; RPLP1; RPLP0; RPL22; RPL18; RPL7; PHB; NPM1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Sheep: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

48kDa

Shipping Conditions

Wet Ice

Protein Length

458

NCBI Gene Symbol

CD4

NCBI GB Accession Number

CD4

Host or Source

Rabbit

Protein Name

T-cell surface glycoprotein CD4

Nucleotide Accession Number

NM_000616

Peptide Sequence

VLGGVAGLLLFIGLGIFFCVRCRHRRRQAERMSQIKRLLSEKKTCQCPHR

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