CD4 Antibody - C-terminal region : Biotin (ARP59105_P050-Biotin)
Selected Variant
ARP59105_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
CD4 molecule
Gene Aliases
IMD79, OKT4D, CD4mut
Gene ID
920
Swiss Prot
P01730
Accession Number
NP_000607
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human CD4
Target
This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Partner Proteins
Env; RANBP9; vpu; ADRB2; UBC; CXCR4; UBL7; ABCB1; INPPL1; VCP; HGS; LCK; NR3C1; STUB1; TUBB; MYL12A; DHRS2; LRPPRC; FARSB; EIF3I; EIF3D; EIF3C; EIF3B; VIM; VDAC3; VDAC2; VDAC1; SSRP1; RPS19; RPS12; RPS10; RPS9; RPLP1; RPLP0; RPL22; RPL18; RPL7; PHB; NPM1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Sheep: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
48kDa
Shipping Conditions
Wet Ice
Protein Length
458
NCBI Gene Symbol
CD4
NCBI GB Accession Number
CD4
Host or Source
Rabbit
Protein Name
T-cell surface glycoprotein CD4
Nucleotide Accession Number
NM_000616
Peptide Sequence
VLGGVAGLLLFIGLGIFFCVRCRHRRRQAERMSQIKRLLSEKKTCQCPHR
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