CD3E Antibody - middle region: Biotin (ARP59097_P050-Biotin)
Product Specifications
Gene Name
CD3e molecule, epsilon (CD3-TCR complex)
Gene Aliases
T3E, TCRE, IMD18
Gene ID
916
Swiss Prot
P07766
Accession Number
NP_000724
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human CD3E
Target
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
Partner Proteins
UBC; CSK; ZAP70; SNTA1; PTPN22; PIK3R2; PIK3R1; LAT; LCK; CD38; CD247; CD3G; TRAT1; NCK2; UNC119; SHC1; NCK1; SYK; CD3D; NCL; CD79B; TOP2B; CD3EAP; JAK3
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
23kDa
Shipping Conditions
Wet Ice
Protein Length
207
NCBI Gene Symbol
CD3E
Protein Name
T-cell surface glycoprotein CD3 epsilon chain
Nucleotide Accession Number
NM_000733
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