IL7R Antibody - middle region : HRP (ARP59084_P050-HRP)

The protein encoded by this gene is a receptor for interleukine 7 (IL7) . The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V (D) J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID) .

KIT; JAK3; SNRPG; SNRPD3; SNRPD2; SNRPD1; SNRPB; SNRPA; SNRNP70; SRSF3; SAFB; RPS20; RPS3; RPL31; RPL29; RPL30; RPL22; RPL18; RPL15; RPL8; RPL7; RPL6; RBM3; PURB; PURA; PTMA; PTBP1; EIF2AK2; YBX1; NONO; NCL; MAP4; RPSA; ILF3; ILF2; HNRNPU; HNRNPL; HNRNPH3

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.