Atg7 Antibody - C-terminal region : Biotin (ARP59072_P050-Biotin)
Selected Variant
ARP59072_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Autophagy related 7
Gene Aliases
Apg7l
Gene ID
312647
Swiss Prot
Q641Y5
Accession Number
NP_001012097
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Rat Atg7
Target
Atg7 functions as an E1 enzyme essential for multisubstrates such as ATG8-like proteins and ATG12. It forms intermediate conjugates with ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A) . PE-conjugation to ATG8-like proteins is essential for autophagy. It also acts as an E1 enzyme for ATG12 conjugation to ATG5 and ATG3.
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 86%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
76kDa
Shipping Conditions
Wet Ice
Protein Length
698
NCBI Gene Symbol
ATG7
NCBI GB Accession Number
Atg7
Host or Source
Rabbit
Protein Name
Ubiquitin-like modifier-activating enzyme ATG7
Nucleotide Accession Number
NM_001012097
Peptide Sequence
KLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPSHLVAPADLGSSLFANI
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