AXL Antibody - C-terminal region : Biotin (ARP59004_P050-Biotin)
Selected Variant
ARP59004_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
AXL receptor tyrosine kinase
Gene Aliases
ARK, UFO, JTK11, Tyro7
Gene ID
558
Swiss Prot
P30530
Accession Number
NP_001690
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human AXL
Target
The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.
Partner Proteins
RANBP9; UBC; TYRO3; FBXO25; STUB1; HSP90AA1; HSPA1A; ERRFI1; TNK2; ELAVL1; CBL; SHC3; SOCS1; PIK3R2; ADAM10; SHC1; GAS6; SRC; PTPN11; PLCG1; PIK3R1; LCK; AXL; GRB2; TENC1; PIK3R3; NCK2
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 79%; Dog: 79%; Guinea Pig: 85%; Horse: 93%; Human: 100%; Mouse: 85%; Pig: 86%; Rat: 85%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
97kDa
Shipping Conditions
Wet Ice
Protein Length
885
NCBI Gene Symbol
AXL
NCBI GB Accession Number
AXL
Host or Source
Rabbit
Protein Name
Tyrosine-protein kinase receptor UFO
Nucleotide Accession Number
NM_001699
Peptide Sequence
QPDPKDSCSCLTAAEVHPAGRYVLCPSTTPSPAQPADRGSPAAPGQEDGA
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