CASP10 Antibody - c-terminal region : Biotin (ARP58999_P050-Biotin)

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer.

FADD; PRDX6; XIAP; RB1; Dlg4; PHF20L1; OIP5; ECE2; RIOK3; NFKBIL1; CASP8; RNF34; BFAR; CASP8AP2; MSN2; PTC2; AIM9; GLN3; SLT2; GPA1; STE20; ATG13; RPL21B; VPS30; CUP9; TPK2; GAL4; FAR11; WHI3; ATG4; FAR3; FAR8; ITT1; MPH1; SSM4; ASG1; BFR1; ORT1; MBR1; CW

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.