CASP7 Antibody - N-terminal region : Biotin (ARP58995_P050-Biotin)

Product Specifications

Gene Name

Caspase 7, apoptosis-related cysteine peptidase

Gene Aliases

MCH3, CMH-1, LICE2, CASP-7, ICE-LAP3

Gene ID

840

Swiss Prot

P55210

Accession Number

NP_203124

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CASP7

Target

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms.

Partner Proteins

PTGES3; BAX; PARP1; SAT1; CRYAB; XIAP; RPS6KA1; CTSA; PEPD; MVD; GNS; GBP2; EEF2; CAPN1; CNDP2; GINS2; EIF4H; GZMB; ROCK1; DFFA; CASP9; CASP7; CASP3; ARHGDIA; VIM; STAT1; SPTAN1; CLSPN; PLA2G4B; RB1; UBC; BIRC2; CCT2; VCP; SP1; BIRC3; BIRC6; COPS6; TERF1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

CASP7 is supported by BioGPS gene expression data to be expressed in OVCAR3

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 93%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.