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UCHL1 Antibody - C-terminal region : Biotin (ARP58968_P050-Biotin)

Product Specifications

Gene Name

Ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

Gene Aliases

NDGOA, PARK5, PGP95, SPG79, PGP9.5, Uch-L1, HEL-117, PGP 9.5, HEL-S-53

Gene ID

7345

Swiss Prot

P09936

Accession Number

NP_004172

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human UCHL1

Target

The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.

Partner Proteins

UBC; ERN1; TNFRSF1A; NMRAL1; TRAF6; TRAF3; PMAIP1; CDK6; CDK5; CDK4; CDK1; IQCB1; RPTOR; DDB1; WDR82; TRIM63; USP28; TRIM54; USP21; USP15; NCAM1; AKT1; CDK2; ADRB2; ADRA2C; ADRA2B; ADRA2A; TERF2IP; TINF2; TUBA1A; LAMP2; HSP90AA1; HSPA8; PLA2G2A; CDKN2A; T

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

UCHL1 is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

25kDa

Shipping Conditions

Wet Ice

Protein Length

223

NCBI Gene Symbol

UCHL1

NCBI GB Accession Number

UCHL1

Host or Source

Rabbit

Protein Name

Ubiquitin carboxyl-terminal hydrolase isozyme L1

Nucleotide Accession Number

NM_004181

Peptide Sequence

HLYELDGRMPFPVNHGASSEDTLLKDAAKVCREFTEREQGEVRFSAVALC

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