MYD88 Antibody - middle region : Biotin (ARP58920_P050-Biotin)
Selected Variant
ARP58920_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Myeloid differentiation primary response gene (88)
Gene Aliases
IMD68, MYD88D
Gene ID
4615
Swiss Prot
Q99836-2
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human MYD88
Target
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity purified
Concentration
0.5 mg/ml
Homology
Cow: 86%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%; Sheep: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
27kDa
Shipping Conditions
Wet Ice
Protein Length
251
NCBI Gene Symbol
MYD88
NCBI GB Accession Number
MYD88
Host or Source
Rabbit
Protein Name
Myeloid differentiation primary response protein MyD88
Peptide Sequence
AEEMDFEYLEIRQLETQADPTGRLLDAWQGRPGASVGRLLELLTKLGRDD
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