MYD88 Antibody - middle region : FITC (ARP58919_P050-FITC)

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.

MYD88; IRAK4; IL1R1; IKBKG; SPOP; SYK; SASH1; TRAF6; SIAH2; SIAH1; PFKL; PRDX1; MDM2; MAL; SMAD3; MBIP; TLR7; TNFRSF13B; CD93; IKBKE; POLR1C; IL1RL1; FADD; USP7; TXN; BST2; SMURF1; LRRFIP2; UBC; SMAD6; IRF5; IRAK1; BTK; PELI1; STAP2; TNIP1; TRAF3; IRAK2

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.