MAPK1 Antibody - C-terminal region : Biotin (ARP58899_P050-Biotin)

Product Specifications

Gene Name

Mitogen-activated protein kinase 1

Gene Aliases

ERK, p38, p40, p41, ERK2, ERT1, NS13, ERK-2, MAPK2, PRKM1, PRKM2, P42MAPK, p41mapk, p42-MAPK

Gene ID

5594

Swiss Prot

P28482

Accession Number

NP_620407

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human MAPK1

Target

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.

Partner Proteins

Eif4ebp1; ATF2; RPS6KA3; RAF1; PTGDR; MAP2K6; MAP2K1; MAPK3; HDAC6; TP53; NEDD8; DGCR8; HMGB1; NAV1; PDCD6IP; CEP350; MAPK12; RPS6KA2; MAPK1; PDE4D; MBP; KRAS; SQSTM1; CUEDC2; GAB2; BRAF; RPS6KA1; MAP2K4; MAP2K2; ELK1; NOXA1; TIAL1; GADD45A; MAP3K10; SMAD

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

MAPK1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.