EIF4E2 Antibody - N-terminal region: HRP (ARP58897_P050-HRP)
Product Specifications
Gene Name
Eukaryotic translation initiation factor 4E family member 2
Gene Aliases
4EHP, IF4e, 4E-LP, h4EHP, EIF4EL3
Gene ID
9470
Swiss Prot
O60573
Accession Number
NP_004837
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human EIF4E2
Target
EIF4E2 belongs to the eukaryotic initiation factor 4E family. It recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
Partner Proteins
USHBP1; CARD9; PRDM14; HOMEZ; TRIM54; NECAB2; ADAMTSL4; AMOTL2; SPAG5; SPRY2; HUWE1; TMCC2; MAGED1; TCF4; TADA2A; TRIM27; REL; MYOG; KRT31; KRT19; KRT13; CDR2; AES; MAPRE3; NOTCH2NL; KRTAP10-8; KRTAP10-5; KRTAP10-9; ZBTB9; SPERT; USP54; MIPOL1; KRT40; UBX
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
EIF4E2 is strongly supported by BioGPS gene expression data to be expressed in MCF7 There is BioGPS gene expression data showing that EIF4E2 is expressed in Jurkat
Concentration
0.5 mg/mL
Homology
Cow: 93%; Dog: 86%; Guinea Pig: 93%; Horse: 85%; Human: 100%; Mouse: 79%; Rat: 86%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
28kDa
Shipping Conditions
Wet Ice
Protein Length
245
NCBI Gene Symbol
EIF4E2
Protein Name
Eukaryotic translation initiation factor 4E type 2
Nucleotide Accession Number
NM_004846
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