EIF4E2 Antibody - N-terminal region : Biotin (ARP58897_P050-Biotin)

Product Specifications

Gene Name

Eukaryotic translation initiation factor 4E family member 2

Gene Aliases

4EHP, IF4e, 4E-LP, h4EHP, EIF4EL3

Gene ID

9470

Swiss Prot

O60573

Accession Number

NP_004837

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human EIF4E2

Target

EIF4E2 belongs to the eukaryotic initiation factor 4E family. It recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

Partner Proteins

USHBP1; CARD9; PRDM14; HOMEZ; TRIM54; NECAB2; ADAMTSL4; AMOTL2; SPAG5; SPRY2; HUWE1; TMCC2; MAGED1; TCF4; TADA2A; TRIM27; REL; MYOG; KRT31; KRT19; KRT13; CDR2; AES; MAPRE3; NOTCH2NL; KRTAP10-8; KRTAP10-5; KRTAP10-9; ZBTB9; SPERT; USP54; MIPOL1; KRT40; UBX

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

EIF4E2 is strongly supported by BioGPS gene expression data to be expressed in MCF7 There is BioGPS gene expression data showing that EIF4E2 is expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 86%; Guinea Pig: 93%; Horse: 85%; Human: 100%; Mouse: 79%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.