Bnip3l Antibody - middle region : Biotin (ARP58878_P050-Biotin)
Selected Variant
ARP58878_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
BCL2/adenovirus E1B interacting protein 3-like
Gene Aliases
N, Nix, Nip3L, C86132, D14Ertd719, D14Ertd719e
Gene ID
12177
Swiss Prot
Q9Z2F7
Accession Number
NP_033891
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Target
Bnip3l induces apoptosis. It interacts with viral and cellular anti-apoptosis proteins. It can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. It inhibits apoptosis induced by BNIP3. It is involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. Bnip3l may function as a tumor suppressor.
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
24kDa
Shipping Conditions
Wet Ice
Protein Length
218
NCBI Gene Symbol
BNIP3L
NCBI GB Accession Number
Bnip3l
Host or Source
Rabbit
Protein Name
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
Nucleotide Accession Number
NM_009761
Peptide Sequence
CDSPSPQEDGQIMFDVEMHTSRDHSSQSEEEVVEGEKEVEALKKSADWVS
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