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SHB Antibody - N-terminal region : Biotin (ARP58762_P050-Biotin)

Product Specifications

Gene Name

Src homology 2 domain containing adaptor protein B

Gene Aliases

BA3J10.2

Gene ID

6461

Swiss Prot

Q15464

Accession Number

NP_003019

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SHB

Target

SHB is the adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. SHB may play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. SHB may also play a rol

Partner Proteins

SLC39A1; GRAP2; LAT; LCP2; EPS8; JAK3; IL2RG; KDR; SRC; ZAP70; PDGFRA; PLCG1; PIK3R1; VAV1; CRK; JAK1; IL2RB; GRB2; FGFR1; PDGFRB

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

SHB is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 82%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

55kDa

References & Citations

Kriz, V., (2006) J. Biol. Chem. 281 (45), 34484-34491

Shipping Conditions

Wet Ice

Protein Length

509

NCBI Gene Symbol

SHB

NCBI GB Accession Number

SHB

Host or Source

Rabbit

Protein Name

SH2 domain-containing adapter protein B

Nucleotide Accession Number

NM_003028

Peptide Sequence

MAKWLNKYFSLGNSKTKSPPQPPRPDYREQRRRGERPSQPPQAVPQASSA

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