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TXNDC4 Antibody - middle region : FITC (ARP58726_P050-FITC)

Selected Variant

ARP58726_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Endoplasmic reticulum protein 44

Gene Aliases

PDIA10, TXNDC4

Gene ID

23071

Swiss Prot

Q9BS26

Accession Number

NP_055866

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TXNDC4

Target

TXNDC4 mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. TXNDC4 inhibits the calcium channel activity of ITPR1. TXNDC4 may have a role in the control of oxidative protein folding in the endoplasmic reticulum. TXNDC4 is required to retain ERO1L and ERO1LB in the endoplasmic reticulum.

Partner Proteins

FUS; UBC; SUMO1; NEDD8; NUDCD1; UBFD1; OSGEP; LARS; ISOC1; PLD3; PDCD10; FERMT2; YWHAZ; VCL; PFAS; PAK2; G6PD; FHL2; CNN2; TBCB; CKB; env; ELAVL1; SUMO4; RASSF5; USP32; USP46; UIMC1; ERO1LB; ERO1L; ITPR1; CD40

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 86%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

45kDa

References & Citations

Mariappan, M., (2008) J. Biol. Chem. 283 (10), 6375-6383

Shipping Conditions

Wet Ice

Protein Length

406

NCBI Gene Symbol

ERP44

NCBI GB Accession Number

ERP44

Host or Source

Rabbit

Protein Name

Endoplasmic reticulum resident protein 44

Nucleotide Accession Number

NM_015051

Peptide Sequence

LHREFHHGPDPTDTAPGEQAQDVASSPPESSFQKLAPSEYRYTLLRDRDE

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