TXNDC4 Antibody - middle region : FITC (ARP58726_P050-FITC)
Product Specifications
Gene Name
Endoplasmic reticulum protein 44
Gene Aliases
PDIA10, TXNDC4
Gene ID
23071
Swiss Prot
Q9BS26
Accession Number
NP_055866
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human TXNDC4
Target
TXNDC4 mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. TXNDC4 inhibits the calcium channel activity of ITPR1. TXNDC4 may have a role in the control of oxidative protein folding in the endoplasmic reticulum. TXNDC4 is required to retain ERO1L and ERO1LB in the endoplasmic reticulum.
Partner Proteins
FUS; UBC; SUMO1; NEDD8; NUDCD1; UBFD1; OSGEP; LARS; ISOC1; PLD3; PDCD10; FERMT2; YWHAZ; VCL; PFAS; PAK2; G6PD; FHL2; CNN2; TBCB; CKB; env; ELAVL1; SUMO4; RASSF5; USP32; USP46; UIMC1; ERO1LB; ERO1L; ITPR1; CD40
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 86%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
45kDa
References & Citations
Mariappan, M., (2008) J. Biol. Chem. 283 (10), 6375-6383
Shipping Conditions
Wet Ice
Protein Length
406
NCBI Gene Symbol
ERP44
NCBI GB Accession Number
ERP44
Host or Source
Rabbit
Protein Name
Endoplasmic reticulum resident protein 44
Nucleotide Accession Number
NM_015051
Peptide Sequence
LHREFHHGPDPTDTAPGEQAQDVASSPPESSFQKLAPSEYRYTLLRDRDE
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