TRPC3 Antibody - N-terminal region : FITC (ARP58715_P050-FITC)
Product Specifications
Gene Name
Transient receptor potential cation channel, subfamily C, member 3
Gene Aliases
TRP3, SCA41
Gene ID
7222
Swiss Prot
Q13507
Accession Number
NP_003296
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the n terminal region of human TRPC3
Target
TRPC3 is thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. TRPC3 is activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol-1,4,5-triphosphate receptors (ITPR) with bound IP3. TRPC3 may also be activated by internal calcium store depletion.
Partner Proteins
STX3; TRPC1; PRKG1; ORAI1; PLCB1; PLCB2; TRPC6; NAPA; PLCB3; FKBP1A; VAMP2; SLC8A1; PRKCA; PLCG1; ITPR3; ITPR1; MX1; GNA11; CALM1; TRPC7; TRPC3; TRPC5; TRPC4
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
97kDa
References & Citations
Lof, C., (2008) J. Cell. Physiol. 216 (1), 245-252
Shipping Conditions
Wet Ice
Protein Length
848
NCBI Gene Symbol
TRPC3
NCBI GB Accession Number
TRPC3
Host or Source
Rabbit
Protein Name
Short transient receptor potential channel 3
Nucleotide Accession Number
NM_003305
Peptide Sequence
MEGSPSLRRMTVMREKGRRQAVRGPAFMFNDRGTSLTAEEERFLDAAEYG
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC940679-100 1x 100 µL
CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC880017-500 1x 500 µL
Ep-CAM / CD326 (VU-1D9), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC942227-100 1x 100 µL
GFAP (Astrocyte & Neural Stem Cell Marker) (rASTRO/789), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details