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UCHL3 Antibody - N-terminal region : FITC (ARP58689_P050-FITC)

Selected Variant

ARP58689_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)

Gene Aliases

UCH-L3

Gene ID

7347

Swiss Prot

P15374

Accession Number

NP_005993

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Goat, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human UCHL3

Target

UCHL3 is an ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8.

Partner Proteins

UBC; CDH1; BAG3; LONRF1; TRIM27; TTC9C; NT5DC1; UBR1; UNK; UBL7; ZFYVE19; USP48; UBA6; ZNF593; UBQLN1; VPS33B; UBXN7; AHCYL1; SSSCA1; YAP1; UBE4B; USP34; ZRANB2; ATP6V1F; USP9X; USP5; ZYX; UBE2V1; UBE2L3; UBE2A; TTC1; TSN; SULT1A1; SNRPD1; PCMT1; PBX1; CS

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Goat: 82%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

25kDa

References & Citations

Lim, J., (2006) Cell 125 (4), 801-814

Shipping Conditions

Wet Ice

Protein Length

230

NCBI Gene Symbol

UCHL3

NCBI GB Accession Number

UCHL3

Host or Source

Rabbit

Protein Name

Ubiquitin carboxyl-terminal hydrolase isozyme L3

Nucleotide Accession Number

NM_006002

Peptide Sequence

MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVC

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