UCHL3 Antibody - N-terminal region : Biotin (ARP58689_P050-Biotin)
Product Specifications
Gene Name
Ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
Gene Aliases
UCH-L3
Gene ID
7347
Swiss Prot
P15374
Accession Number
NP_005993
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Goat, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human UCHL3
Target
UCHL3 is an ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8.
Partner Proteins
UBC; CDH1; BAG3; LONRF1; TRIM27; TTC9C; NT5DC1; UBR1; UNK; UBL7; ZFYVE19; USP48; UBA6; ZNF593; UBQLN1; VPS33B; UBXN7; AHCYL1; SSSCA1; YAP1; UBE4B; USP34; ZRANB2; ATP6V1F; USP9X; USP5; ZYX; UBE2V1; UBE2L3; UBE2A; TTC1; TSN; SULT1A1; SNRPD1; PCMT1; PBX1; CS
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Goat: 82%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
25kDa
References & Citations
Lim, J., (2006) Cell 125 (4), 801-814
Shipping Conditions
Wet Ice
Protein Length
230
NCBI Gene Symbol
UCHL3
NCBI GB Accession Number
UCHL3
Host or Source
Rabbit
Protein Name
Ubiquitin carboxyl-terminal hydrolase isozyme L3
Nucleotide Accession Number
NM_006002
Peptide Sequence
MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVC
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