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TSTA3 Antibody - N-terminal region : Biotin (ARP58679_P050-Biotin)

Product Specifications

Gene Name

Tissue specific transplantation antigen P35B

Gene Aliases

FX, P35B, TSTA3, SDR4E1

Gene ID

7264

Swiss Prot

Q13630

Accession Number

NP_003304

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TSTA3

Target

Tissue specific transplantation antigen P35B is a NADP (H) -binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.Tissue specific transplantation antigen P35B is a NADP (H) -binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.

Partner Proteins

UBC; COASY; EFHD2; PPME1; GLRX3; GMPS; RCN1; RBBP7; BAG3; RIOK2; ID2; DNAJC9; DSTN; NEDD4

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

TSTA3 is strongly supported by BioGPS gene expression data to be expressed in 721_B, HeLa TSTA3 is supported by BioGPS gene expression data to be expressed in MCF7

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

35kDa

References & Citations

Roos, C., (2002) J. Biol. Chem. 277 (5), 3168-3175

Shipping Conditions

Wet Ice

Protein Length

321

NCBI Gene Symbol

TSTA3

NCBI GB Accession Number

TSTA3

Host or Source

Rabbit

Protein Name

GDP-L-fucose synthase

Nucleotide Accession Number

NM_003313

Peptide Sequence

MGEPQGSMRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTD

Frequently Asked Questions

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