DDAH2 Antibody - N-terminal region : FITC (ARP58611_P050-FITC)
Product Specifications
Gene Name
Dimethylarginine dimethylaminohydrolase 2
Gene Aliases
G6a, DDAH, NG30, DDAHII, HEL-S-277
Gene ID
23564
Swiss Prot
O95865
Accession Number
NP_039268
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human DDAH2
Target
DDAH2 hydrolyzes N (G), N (G) -dimethyl-L-arginine (ADMA) and N (G) -monomethyl-L-arginine (MMA) which act as inhibitors of NOS. DDAH2 has therefore a role in nitric oxide generation.This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Partner Proteins
VAC14; UBC; TRIP13; VCAM1; FN1; CDC73; TAF1D; ZAK; DNAJB11; GADD45G; RPS6KA5; TSC22D1; TNFSF11; MKNK1; TK1; STK3; SMN1; RPS6KA1; RAP1B; PIN1; RCC1; CDKN1A; CDK4; ATP1B1; ANXA7
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 79%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
31kDa
References & Citations
Kim, Y.J., (2008) Twin Res Hum Genet 11 (1), 77-83
Shipping Conditions
Wet Ice
Protein Length
285
NCBI Gene Symbol
DDAH2
NCBI GB Accession Number
DDAH2
Host or Source
Rabbit
Protein Name
N (G), N (G) -dimethylarginine dimethylaminohydrolase 2
Nucleotide Accession Number
NM_013974
Peptide Sequence
MGTPGEGLGRCSHALIRGVPESLASGEGAGAGLPALDLAKAQREHGVLGG
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