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BUB3 Antibody - N-terminal region : FITC (ARP58599_P050-FITC)

Product Specifications

Gene Name

Budding uninhibited by benzimidazoles 3 homolog (yeast)

Gene Aliases

BUB3L, hBUB3

Gene ID

9184

Swiss Prot

A6NJ42

Accession Number

NP_001007794

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human BUB3

Target

BUB3 is required for kinetochore localization of BUB1.This gene encodes a protein involved in spindle checkpoint function. The encoded protein contains four WD repeat domains and has sequence similarity with the yeast BUB3 protein. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Partner Proteins

BUB1B; BUB1; HUWE1; PSTPIP1; UBC; SUMO2; CDC20; NEDD8; SUMO1; RPA3; RPA2; RPA1; WBP4; CLIP1; EGFR; ZNF207; VCAM1; UBA1; THRA; RPL37A; ITGA4; FN1; NKAP; EXOC3; SUGT1; CPNE1; ANAPC4; SEPT2; TOP1; SMAD3; SMAD2; Mad2l1; COPS5; CUL3; SF3A2; ELAVL1; CDC27; HDGF

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB, IF, IHC

Purification

Affinity Purified

Sample Type

BUB3 is strongly supported by BioGPS gene expression data to be expressed in HEK293T, PANC1

Concentration

0.5 mg/ml

Homology

Cow: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

36kDa

References & Citations

Vaclavicek, A., (2007) Breast Cancer Res. Treat. 106 (2), 205-213

Shipping Conditions

Wet Ice

Protein Length

326

NCBI Gene Symbol

BUB3

NCBI GB Accession Number

BUB3

Host or Source

Rabbit

Protein Name

Mitotic checkpoint protein BUB3

Nucleotide Accession Number

NM_001007793

Peptide Sequence

MTGSNEFKLNQPPEDGISSVKFSPNTSQFLLVSSWDTSVRLYDVPANSMR

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