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WARS Antibody - N-terminal region : Biotin (ARP58550_P050-Biotin)

Product Specifications

Gene Name

Tryptophanyl-tRNA synthetase

Gene Aliases

HMN9, WARS, IFI53, IFP53, GAMMA-2

Gene ID

7453

Swiss Prot

P23381

Accession Number

NP_004175

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human WARS

Target

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA (trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family.Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA (trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene.

Partner Proteins

UBC; SUMO2; CDC34; CALU; ADSL; AARS; CTPS2; HERC4; NT5C2; FKBP9; EHD1; GNPDA1; GTF3C4; USP5; XPNPEP1; RAD23A; TWF1; PCNA; NUCB1; KTN1; GTF2I; CD81; LIG4; TRIM25; GART; APP; ISG15; TERF1; SIRT7; PSMA3; DNMT3B; DCAF13; DDA1; GBAS; CDK2AP2; MDH2; EEF1A1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

52kDa

References & Citations

Shen, N., (2008) Nucleic Acids Res. 36 (4), 1288-1299

Shipping Conditions

Wet Ice

Protein Length

471

NCBI Gene Symbol

WARS

NCBI GB Accession Number

WARS

Host or Source

Rabbit

Protein Name

Tryptophan--tRNA ligase, cytoplasmic

Nucleotide Accession Number

NM_004184

Peptide Sequence

EIDSAVKMLVSLKMSYKAAAGEDYKADCPPGNPAPTSNHGPDATEAEEDF

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