WARS Antibody - N-terminal region : Biotin (ARP58550_P050-Biotin)
Product Specifications
Gene Name
Tryptophanyl-tRNA synthetase
Gene Aliases
HMN9, WARS, IFI53, IFP53, GAMMA-2
Gene ID
7453
Swiss Prot
P23381
Accession Number
NP_004175
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human WARS
Target
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA (trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family.Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA (trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene.
Partner Proteins
UBC; SUMO2; CDC34; CALU; ADSL; AARS; CTPS2; HERC4; NT5C2; FKBP9; EHD1; GNPDA1; GTF3C4; USP5; XPNPEP1; RAD23A; TWF1; PCNA; NUCB1; KTN1; GTF2I; CD81; LIG4; TRIM25; GART; APP; ISG15; TERF1; SIRT7; PSMA3; DNMT3B; DCAF13; DDA1; GBAS; CDK2AP2; MDH2; EEF1A1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
52kDa
References & Citations
Shen, N., (2008) Nucleic Acids Res. 36 (4), 1288-1299
Shipping Conditions
Wet Ice
Protein Length
471
NCBI Gene Symbol
WARS
NCBI GB Accession Number
WARS
Host or Source
Rabbit
Protein Name
Tryptophan--tRNA ligase, cytoplasmic
Nucleotide Accession Number
NM_004184
Peptide Sequence
EIDSAVKMLVSLKMSYKAAAGEDYKADCPPGNPAPTSNHGPDATEAEEDF
Frequently Asked Questions
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