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HNRPH1 Antibody - middle region : Biotin (ARP58479_P050-Biotin)

Product Specifications

Gene Name

Heterogeneous nuclear ribonucleoprotein H1 (H)

Gene Aliases

HNRPH, HNRPH1, hnRNPH

Gene ID

3187

Swiss Prot

P31943

Accession Number

NP_005511

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human HNRPH1

Target

HNRPH1 belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. This protein has three repeats of quasi-RRM domains that bind to RNAs. It is very similar to the family member HNRPF. This gene is thought to be potentially involved in hereditary lymphedema type I phenotype.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. It is very similar to the family member HNRPF. This gene is thought to be potentially involved in hereditary lymphedema type I phenotype. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

HUWE1; UBC; FUS; CEP76; CEP250; VCP; TP53; SUMO2; SUMO3; TUBGCP3; STAU1; MDM2; RPA3; RPA2; RPA1; ERG; ASB2; EED; rev; APBB1; AASDHPPT; IPO11; TNPO3; PEG10; PSMD9; PPP3CA; PPP2CA; PIN1; PARK2; PARP1; FBXO6; TARDBP; YWHAQ; ADRB2; IGSF8; ICAM1; CD81; PAN2; U

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IF, IP, WB, IHC

Purification

Affinity Purified

Sample Type

HNRNPH1 is strongly supported by BioGPS gene expression data to be expressed in 721_B, Jurkat, MCF7 HNRNPH1 is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

49kDa

References & Citations

Olsen, J.V., (2006) Cell 127 (3), 635-648

Shipping Conditions

Wet Ice

Protein Length

449

NCBI Gene Symbol

HNRNPH1

NCBI GB Accession Number

HNRNPH1

Host or Source

Rabbit

Protein Name

Heterogeneous nuclear ribonucleoprotein H

Nucleotide Accession Number

NM_005520

Peptide Sequence

FLNSTAGASGGAYEHRYVELFLNSTAGASGGAYGSQMMGGMGLSNQSSYG

Frequently Asked Questions

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