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FKBP2 Antibody - N-terminal region : Biotin (ARP58465_P050-Biotin)

Selected Variant

ARP58465_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

FK506 binding protein 2, 13kDa

Gene Aliases

FKBP13, PPIase, FKBP-13

Gene ID

2286

Swiss Prot

P26885

Accession Number

NP_004461

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human FKBP2

Target

FKBP2 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. This gene has two alternatively spliced transcript variants that encode the same isoform. Multiple polyadenylation sites have been described for this gene, but the full length nature of this gene has not been determined.

Partner Proteins

UBQLN1; RAB3C; VAMP2; RAB6A; UBC; BARD1; UBQLN4; PTGES3; RAP2A; MAPK3; ARFGEF1; EPB41L2; BAG6; EPB41; C1QC; ARFGEF2; CDKN2A

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

FKBP2 is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

16kDa

References & Citations

Lim, J., (2006) Cell 125 (4), 801-814

Shipping Conditions

Wet Ice

Protein Length

142

NCBI Gene Symbol

FKBP2

NCBI GB Accession Number

FKBP2

Host or Source

Rabbit

Protein Name

Peptidyl-prolyl cis-trans isomerase FKBP2

Nucleotide Accession Number

NM_004470

Peptide Sequence

RLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDV

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