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CPE Antibody - N-terminal region : Biotin (ARP58445_P050-Biotin)

Product Specifications

Gene Name

Carboxypeptidase E

Gene Aliases

CPH

Gene ID

1363

Swiss Prot

P16870

Accession Number

NP_001864

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CPE

Target

CPE is a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteinsThis gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

PRKAA1; UBC; LRIF1; POLDIP2; MED31; ROBO2; POLA2; CHD3; TRH; NTS; GTF3C1; UTP14A; RPA1; PMCH; INS; GCG; GAST; CCK; BDNF

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

CPE is strongly supported by BioGPS gene expression data to be expressed in HepG2 CPE is supported by BioGPS gene expression data to be expressed in MCF7

Concentration

0.5 mg/ml

Homology

Cow: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

52kDa

References & Citations

Wang, J., (2008) Acta Pharmacol. Sin. 29 (6), 736-744

Shipping Conditions

Wet Ice

Protein Length

476

NCBI Gene Symbol

CPE

NCBI GB Accession Number

CPE

Host or Source

Rabbit

Protein Name

Carboxypeptidase E

Nucleotide Accession Number

NM_001873

Peptide Sequence

GMRRRRRLQQEDGISFEYHRYPELREALVSVWLQCTAISRIYTVGRSFEG

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