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CAPNS1 Antibody - middle region : HRP (ARP58434_P050-HRP)

Selected Variant

ARP58434_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Calpain, small subunit 1

Gene Aliases

CANP, CDPS, CSS1, CANPS, CAPN4, CALPAIN4

Gene ID

826

Swiss Prot

P04632

Accession Number

NP_001003962

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CAPNS1

Target

Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene.

Partner Proteins

AGTRAP; HUWE1; NEDD1; TUBGCP2; TUBGCP3; CDC20; UBC; OGFOD1; STK26; ISOC1; DCPS; MAT2B; PROSC; FERMT2; YWHAQ; PDIA4; YWHAZ; YWHAH; YWHAG; YWHAE; PTMA; PPP1CA; PAK2; PAFAH1B1; MYO1E; MAT2A; GNAI3; GAPDH; EIF5; TBCB; ALDH7A1; ASNS; APEX1; ADRB2; PPARGC1A; VC

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

29kDa

Shipping Conditions

Wet Ice

Protein Length

268

NCBI Gene Symbol

CAPNS1

NCBI GB Accession Number

CAPNS1

Host or Source

Rabbit

Protein Name

Calpain small subunit 1

Nucleotide Accession Number

NM_001003962

Peptide Sequence

RRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQL

Subunit

1

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