CAPNS1 Antibody - middle region : Biotin (ARP58434_P050-Biotin)

Product Specifications

Gene Name

Calpain, small subunit 1

Gene Aliases

CANP, CDPS, CSS1, CANPS, CAPN4, CALPAIN4

Gene ID

826

Swiss Prot

P04632

Accession Number

NP_001003962

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CAPNS1

Target

Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene.

Partner Proteins

AGTRAP; HUWE1; NEDD1; TUBGCP2; TUBGCP3; CDC20; UBC; OGFOD1; STK26; ISOC1; DCPS; MAT2B; PROSC; FERMT2; YWHAQ; PDIA4; YWHAZ; YWHAH; YWHAG; YWHAE; PTMA; PPP1CA; PAK2; PAFAH1B1; MYO1E; MAT2A; GNAI3; GAPDH; EIF5; TBCB; ALDH7A1; ASNS; APEX1; ADRB2; PPARGC1A; VC

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.