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CA1 Antibody - N-terminal region : HRP (ARP58432_P050-HRP)

Selected Variant

ARP58432_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Carbonic anhydrase I

Gene Aliases

CAB, CA-I, Car1, HEL-S-11

Gene ID

759

Swiss Prot

P00915

Accession Number

NP_001729

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Guinea Pig, Pig, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CA1

Target

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Transcript variants of CA1 utilizing alternative polyA_sites have been described in literature.

Partner Proteins

TFCP2; HSD17B7; MAPK6

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 86%; Guinea Pig: 79%; Human: 100%; Pig: 100%; Rat: 79%; Sheep: 79%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

29kDa

References & Citations

Gambhir, K.K., Biochem. Genet. 45 (5-6), 431-439 (2007)

Shipping Conditions

Wet Ice

Protein Length

261

NCBI Gene Symbol

CA1

NCBI GB Accession Number

CA1

Host or Source

Rabbit

Protein Name

Carbonic anhydrase 1

Nucleotide Accession Number

NM_001738

Peptide Sequence

ASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVS

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