CA1 Antibody - N-terminal region : FITC (ARP58432_P050-FITC)
Product Specifications
Gene Name
Carbonic anhydrase I
Gene Aliases
CAB, CA-I, Car1, HEL-S-11
Gene ID
759
Swiss Prot
P00915
Accession Number
NP_001729
Host
Rabbit
Reactivity
Human, Rat, Cow, Dog, Guinea Pig, Pig, Sheep
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human CA1
Target
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Transcript variants of CA1 utilizing alternative polyA_sites have been described in literature.
Partner Proteins
TFCP2; HSD17B7; MAPK6
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 79%; Dog: 86%; Guinea Pig: 79%; Human: 100%; Pig: 100%; Rat: 79%; Sheep: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
29kDa
References & Citations
Gambhir, K.K., Biochem. Genet. 45 (5-6), 431-439 (2007)
Shipping Conditions
Wet Ice
Protein Length
261
NCBI Gene Symbol
CA1
NCBI GB Accession Number
CA1
Host or Source
Rabbit
Protein Name
Carbonic anhydrase 1
Nucleotide Accession Number
NM_001738
Peptide Sequence
ASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVS
Frequently Asked Questions
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