CDC2 Antibody - middle region: Biotin (ARP58401_P050-Biotin)
Product Specifications
Gene Name
Cyclin-dependent kinase 1
Gene Aliases
CDC2, CDC28A, P34CDC2
Gene ID
983
Swiss Prot
P06493
Accession Number
NP_203698
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human CDC2
Target
The protein encoded by CDC2 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
Partner Proteins
ABL1; SIRT1; CDC37; HUWE1; BTRC; UBC; HSP90AA1; HSPA4; HIST1H1A; GADD45A; CKS1B; USP16; Samhd1; UIMC1; SUMO2; CCNA2; STAU1; RNF2; CKS2; ZRANB2; CDKN1B; CDKN1A; CDK1; CCNB1; FBXO6; CCNB2; PKMYT1; SQSTM1; EGFR; PTMA; DCTN6; RGCC; BAG3; CDC25B; BCL2; TP53BP1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 83%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
27kDa
Shipping Conditions
Wet Ice
Protein Length
240
NCBI Gene Symbol
CDK1
Protein Name
Cyclin-dependent kinase 1
Nucleotide Accession Number
NM_033379
Curated Selection
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