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CBX2 Antibody - middle region: FITC (ARP58370_P050-FITC)

Product Specifications

Gene Name

Chromobox homolog 2

Gene Aliases

M33, CDCA6, SRXY5

Gene ID

84733

Swiss Prot

Q14781

Accession Number

NP_005180

Host

Rabbit

Reactivity

Human, Rat, Cow, Horse, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CBX2

Target

CBX2 Contains 1 A.T hook DNA-binding domain and 1 chromo domain. CBX2 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Partner Proteins

KRTAP10-3; KRTAP10-1; KRTAP10-9; KRTAP10-7; RBMY1F; DHX57; KRTAP2-4; RBMY1A1; RNF2; BMI1; MDFI; SOX2; GTF2I; PHC2; CSNK2B; CSNK2A2; CSNK2A1; CENPE; PARP1; CCDC158; DIS3L2; HIST4H4; CBX2; PARP12; RNF213; ZKSCAN7; DCAF6; KDM3A; MYCBP2; ANKRD26; PSME3; TRANK

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

CBX2 is supported by BioGPS gene expression data to be expressed in OVCAR3

Concentration

0.5 mg/mL

Homology

Cow: 86%; Horse: 93%; Human: 100%; Pig: 79%; Rat: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

56kDa

Shipping Conditions

Wet Ice

Protein Length

532

NCBI Gene Symbol

CBX2

Protein Name

Chromobox protein homolog 2

Nucleotide Accession Number

NM_005189

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