CBX2 Antibody - middle region: Biotin (ARP58370_P050-Biotin)
Product Specifications
Gene Name
Chromobox homolog 2
Gene Aliases
M33, CDCA6, SRXY5
Gene ID
84733
Swiss Prot
Q14781
Accession Number
NP_005180
Host
Rabbit
Reactivity
Human, Rat, Cow, Horse, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human CBX2
Target
CBX2 Contains 1 A.T hook DNA-binding domain and 1 chromo domain. CBX2 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Partner Proteins
KRTAP10-3; KRTAP10-1; KRTAP10-9; KRTAP10-7; RBMY1F; DHX57; KRTAP2-4; RBMY1A1; RNF2; BMI1; MDFI; SOX2; GTF2I; PHC2; CSNK2B; CSNK2A2; CSNK2A1; CENPE; PARP1; CCDC158; DIS3L2; HIST4H4; CBX2; PARP12; RNF213; ZKSCAN7; DCAF6; KDM3A; MYCBP2; ANKRD26; PSME3; TRANK
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
CBX2 is supported by BioGPS gene expression data to be expressed in OVCAR3
Concentration
0.5 mg/mL
Homology
Cow: 86%; Horse: 93%; Human: 100%; Pig: 79%; Rat: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
56kDa
Shipping Conditions
Wet Ice
Protein Length
532
NCBI Gene Symbol
CBX2
Protein Name
Chromobox protein homolog 2
Nucleotide Accession Number
NM_005189
Curated Selection
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